Monday, May 10, 2010

AIIMS/AIPGME

QUESTION 3#All of the following are used in treatment of Carbamate poisoning except:

a. Atropine
b. Pralidoxime
c. Supportive measures
d. None of the above

ANSWER: b, Pralidoxime a cholinesterase reactivator...It can be used that can be used for organophosphate poisoning... But not for the carbamates group as in carbamates the anionic site where the drug pralidoxime binds is not free unlike in OP's..Also The drug s also found to have slight intrinsic anticholinesterase activity.. SO it is infact contraindicated in above situation....

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