On 5 September 2008, it was revealed Borgonovo was suffering from amyotrophic lateral sclerosis, the same illness that slowly killed Gianluca Signorini, another former Serie A player, in 2002.
To raise funds and awareness of the disease, a testimonial match was organized by Borgonovo's former clubs Fiorentina and Milan. The game,called "Everyone for Stefano" was played on 8 October 2008 at
At the conclusion of the match, Stefano Borgonovo had a message for every one of the individuals in his situation. “I wanted to say to those who suffer from what I suffer, believe in yourself, believe in football, and believe in the players and the football leagues that will help to find a cure for our illness.”
Investigation is still going on regarding the spread of this disease among Italian soccer players. So far more than 40 Italian ex-football players have been victims of ALS. One theory suggests the link of pesticides on the stadium grass, but so far nothing has been confirmed....